ABSTRACT
@#AIM: To assess corneal endothelial cells and corneal thickness in congenital cataract patients, which contributes to studying the characteristics and mechanism of the disease.<p>METHODS: From August 2014 to December 2018, 141 patients diagnosed with congenital cataract before surgery in our hospital were analyzed retrospectively. Their endothelial cell density(ECD), average size(AVE), standard deviation of size(SD), coefficient of variation(CV), Hexagonality(Hex)and central corneal thickness(CCT)were measured with non-contact specular microscope. The data were statistically analyzed using partial correlation analysis to detect the correlation among patients' ECD, AVE, SD, CV, Hex, CCT and age, and we conducted curve fitting with multiple stepwise regression. We compared male and female patients', bilateral and unilateral cataract's parameters above by covariance analysis.<p>RESULTS: The correlation between patients' ECD, AVE, SD and age was significant, and the fitting curve was obtained with equation ECD=3957.33-306.62×ln(age)、AVE=178.77+27.39×ln(age)and SD=77.13×e0.013×age respectively. CV was significantly greater in female patients than that in male patients(<i>P</i>=0.044). SD and CV was significantly greater in right eyes of bilateral cataract than that in affected eyes(<i>P</i>=0.037, <i>P</i>=0.028 respectively)and healthy eyes(<i>P</i>=0.007, <i>P</i>=0.003 respectively)from unilateral cataract, Hex was significantly less in right eyes of bilateral cataract than that in affected eyes(<i>P</i>=0.006)and healthy eyes(<i>P</i>=0.009)from unilateral cataract, CCT was significantly greater in right eyes of bilateral cataract than that in healthy eyes(<i>P</i>=0.041)from unilateral cataract.<p>CONCLUSION: Congenital cataract may affect corneal endothelial cells and corneal thickness, especially SD, CV, Hex and CCT. Patients' ECD, AVE and SD changes with age. Female patients may have greater CV than male patients.
ABSTRACT
@#AIM: To investigate the necessity of visual acuity, intraocular pressure(IOP)and slit lamp microscope examination on the same day after cataract surgery, and to explore a safe and effective method for postoperative observation.<p>METHODS: We collected cataract patients receiving day surgery from October to November 2018. They underwent phacoemulsification combined with intraocular lens(IOL)implantation. 149 patients(149 eyes)were included. Before the surgery, and 2h, 1d, 1wk after the surgery, we measured and compared their best corrected visual acuity(BCVA)and IOP, observing whether they had the corneal edema, IOL dislocation or other complications with slit lampmicroscope. We also compared the percentage of high IOP, low IOP before and after surgery.<p>RESULTS: BCVA before and 2h after surgery, BCVA 2h and 1d after surgery, and BCVA 1d and 1wk after surgery were statistically different, showing a gradually improving trend(<i>P</i><0.05). There was no significant difference between IOP before surgery and 2h after surgery or 1d after surgery(<i>P</i>>0.05), but the IOP 1wk after surgery was lower than that before surgery, 2h after surgery and 1d after surgery(<i>P</i><0.05). The percentage of high IOP 2h after surgery was significantly higher than that before surgery, 1d after surgery and 1wk after surgery. No ocular complication was found 1wk after surgery.<p>CONCLUSION: The visual acuity, IOP and corneal edema of the patients recovered 1wk after day cataract surgery, and high IOP was easy to happen 2h after surgery. Visual acuity, IOP and slit lamp microscope examination were safe, and corresponding treatment could be given to patients with high IOP.